Document Detail

Epidemiologic, socioeconomic, and clinical factors associated with severity of respiratory syncytial virus infection in previously healthy infants.
MedLine Citation:
PMID:  16928839     Owner:  NLM     Status:  MEDLINE    
We prospectively quantified disease severity associated with epidemiologic and socioeconomic parameters as well as the clinical factors in 195 previously healthy infants with confirmed respiratory syncytial virus (RSV) infection. Infants were enrolled into three subgroups according to disease severity: outpatients (82 patients), inpatients (100 patients), and intensive care unit patients (13 patients). Epidemiologic parameters such as gestational age, birth weight, chronologic age at presentation, and gender as well as socioeconomic factors such as ethnic origin, family history of asthma, exposure to cigarette smoke, number of family members, presence of pets at home, breast-feeding, and day-care attendance were not found to predict the severity of RSV illness in previously healthy infants. Our results emphasize the complexity of predicting disease severity in previously healthy infants with RSV infection and suggest that other parameters such as host genetic background might explain the clinical variability.
Raz Somech; Guy Tal; Eli Gilad; Avigdor Mandelberg; Asher Tal; Ilan Dalal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  45     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-24     Completed Date:  2007-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  621-7     Citation Subset:  AIM; IM    
Department of Pediatrics, Dana Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.
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MeSH Terms
Cohort Studies
Prospective Studies
Respiratory Syncytial Virus Infections / diagnosis*,  epidemiology*
Severity of Illness Index*
Socioeconomic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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