| Epidemiologic evidence supporting the role of maternal vitamin D deficiency as a risk factor for the development of infantile autism. | |
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MedLine Citation:
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PMID: 20592795 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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This study examines whether maternal vitamin D deficiency is a risk factor for infantile autism disease (IAD). We used epidemiologic data seasonal variation of birth rates and prevalence of IAD for cohorts born before 1985. For seven studies reporting spring-to-summer excess birth rates for IAD, the season progressed from broad near 30 degrees N latitude, spring/summer in midlatitudes, to winter at the highest latitude. Also, using data from 10 studies, we found a strong effective latitudinal (related to wintertime solar ultraviolet B radiation) increase in IAD prevalence. These findings are consistent with maternal vitamin D deficiency's being a risk factor for IAD, possibly by affecting fetal brain development as well as possibly by affecting maternal immune system status during pregnancy. Further investigation of this hypothesis is warranted. |
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Authors:
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William B Grant; Connie M Soles |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Dermato-endocrinology Volume: 1 ISSN: 1938-1980 ISO Abbreviation: Dermatoendocrinol Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2010-07-01 Completed Date: 2011-07-14 Revised Date: 2013-05-29 |
Medline Journal Info:
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Nlm Unique ID: 101495367 Medline TA: Dermatoendocrinol Country: United States |
Other Details:
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Languages: eng Pagination: 223-8 Citation Subset: - |
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Erratum In:
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Dermatoendocrinol. 2009 Nov;1(6):314 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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