Document Detail

Epidemiologic assessment of the role of blood pressure in stroke: the Framingham Study. 1970.
MedLine Citation:
PMID:  8849757     Owner:  NLM     Status:  MEDLINE    
Control of hypertension, labile or fixed, systolic or diastolic, at any age, in either sex appears to be central to prevention of atherothrombotic brain infarction (ABI). Prospectively, hypertension proved the most common and potent precursor of ABI's. Its contribution was direct and could not be attributed to factors related both to stroke and hypertension. Asymptomatic, causal "hypertension" was associated with a risk of ABI about four times that of normotensives. The probability of occurrence of an ABI was predicted no better with both blood pressure measurements or the mean arterial pressure than with systolic alone. Since there was no diminishing impact of systolic pressure with advancing age, the concept that systolic elevations are, even in the aged, innocuous is premature. Comparing normotensives and hypertensives in each sex, women did not tolerate hypertension better than men.
W B Kannel; P A Wolf; J Verter; P M McNamara
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Publication Detail:
Type:  Biography; Classical Article; Historical Article; Journal Article    
Journal Detail:
Title:  JAMA     Volume:  276     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1996-11-01     Completed Date:  1996-11-01     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1269-78     Citation Subset:  AIM; IM; Q    
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MeSH Terms
Blood Pressure*
Cerebrovascular Disorders / epidemiology,  etiology,  history*
History, 20th Century
Hypertension / complications,  history*
Middle Aged
Risk Factors
Comment In:
JAMA. 1996 Oct 16;276(15):1279-80   [PMID:  8849758 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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