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Epidemiologic Study of Malassezia Yeasts in Acne Patients by Analysis of 26S rDNA PCR-RFLP.
MedLine Citation:
PMID:  21909202     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although acne is a common follicular inflammatory dermatosis, studies of the relationship between Malassezia yeasts and acne have rarely been conducted.
OBJECTIVE: We sought to identify Malassezia yeasts from acne patients and establish a relationship between specific types of species of Malassezia and acne.
METHODS: Sixty acne patients were enrolled. Each strain obtained was identified as one of eleven species by 26S rDNA PCR-RFLP. We then compared these data with those of age- and sex-matched healthy subjects.
RESULTS: Growth of Malassezia was evident in fewer patients with acne (50%) in comparison to controls (70.6%). M. restricta was dominant in patients with acne (23.9%), whereas M. globosa was most common (26.7%) in healthy controls. In the patients group, the rate was the highest (71.7%) in the twenties and, in terms of body site, the rate was the highest (60%) in the chest. In the control group, the rate was the highest (75.0%) in the thirties and in the forehead (85.0%).
CONCLUSION: The detection rate of Malassezia yeasts was conspicuously low in the acne patients group. Statistically significant differences were observed between the patient and the control groups in the twenties and thirties, and in terms of body site, in the forehead and chest.
Authors:
Young Chan Song; Hyung Jin Hahn; Ji Young Kim; Jong Hyun Ko; Yang Won Lee; Yong Beom Choe; Kyu Joong Ahn
Publication Detail:
Type:  Journal Article     Date:  2011-08-06
Journal Detail:
Title:  Annals of dermatology     Volume:  23     ISSN:  2005-3894     ISO Abbreviation:  Ann Dermatol     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-09-12     Completed Date:  2011-11-10     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8916577     Medline TA:  Ann Dermatol     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  321-8     Citation Subset:  -    
Affiliation:
Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
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