Document Detail

Epidemic enteropathogenic Escherichia coli, Newfoundland, 1963: autopsy study of 16 cases.
MedLine Citation:
PMID:  5335293     Owner:  NLM     Status:  MEDLINE    
The autopsy findings and certain other features are described in 16 fatal cases of infantile diarrhea associated with enteropathogenic Escherichia coli infection during the 1963 epidemic in Newfoundland which resulted in 100 deaths. Age is an important factor in the severity of the infection and in the outcome. Almost one-half the patients were under 4 months and a third under 2 months. Pathological changes in the gastrointestinal tract were meagre and were not pathognomonic. Other pathological findings and their possible role in the severity and fatal outcome in enteropathogenic Escherichia coli gastroenteritis are discussed. Such conditions as prematurity, congenital anomaly, trauma, neoplasm and metabolic disorders were, no doubt, also important factors in the outcome. Severe respiratory tract infection was the leading terminal cause of death. No sex, seasonal or geographic variation was found. Enteropathogenic Escherichia coli serotype 0111:B4 was the prevalent infecting organism.
Y M Rho; J E Josephson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  96     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1967 Feb 
Date Detail:
Created Date:  1967-04-18     Completed Date:  1967-04-18     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  392-8     Citation Subset:  AIM; IM    
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MeSH Terms
Body Weight
Diarrhea, Infantile / mortality*,  pathology*
Disease Outbreaks
Escherichia coli / isolation & purification
Escherichia coli Infections / epidemiology*,  mortality*
Newfoundland and Labrador
Respiratory Tract Infections / mortality*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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