Document Detail

Epidemic dropsy--a clinical study of the Delhi outbreak.
MedLine Citation:
PMID:  11198785     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A major outbreak of epidemic dropsy occurred in Delhi, India, in August-September 1998, due to the consumption of contaminated mustard oil. METHODS: The clinical data of 212 adult patients of epidemic dropsy who presented to our hospital is analysed. RESULTS: Pitting pedal oedema (100%), skin erythema (75%), limb tenderness (63%), diarrhea (51%) and hepatomegaly (34%) were the prominent clinical manifestations observed in the patients. Superficial retinal haemorrhages and retinal venous dilatation was observed on fundus examination and 9% of patients developed an open angle glaucoma over a three month follow up period. Cardiac failure was present in 14% of patients. Most patients had mild disease which responded to cessation of mustard oil consumption, bed rest, diuretics and antioxidants. There were six deaths, all of whom had intractable cardiac failure. A unique feature of this outbreak was the documentation of acute renal failure in three patients, a phenomenon never described previously. CONCLUSIONS: Strict law enforcement to prevent the contamination of edible oils is essential to avoid the occurrence of future similar outbreaks.
N P Singh; S Anuradha; D K Dhanwal; K Singh; A Prakash; K Madan; S K Agarwal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  48     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2001-01-29     Completed Date:  2001-04-12     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  877-80     Citation Subset:  IM    
Department of Medicine, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi-110002, India.
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MeSH Terms
Disease Outbreaks*
Edema / blood,  chemically induced*,  epidemiology*,  therapy
Food Contamination / prevention & control*
India / epidemiology
Middle Aged
Mustard Plant
Plant Extracts / adverse effects*
Plant Oils
Reg. No./Substance:
0/Plant Extracts; 0/Plant Oils; 8007-40-7/mustard oil
Comment In:
J Assoc Physicians India. 2001 Oct;49:1041-2   [PMID:  11848317 ]

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