Document Detail


The Epidemic of the 20(th) Century: Coronary Heart Disease.
MedLine Citation:
PMID:  24811552     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Heart disease was an uncommon cause of death in the US at the beginning of the 20th century. By mid-century it had become the commonest cause. After peaking in the mid 1960s , the number of heart disease deaths began a marked decline that has persisted to the present. The increase in heart disease deaths from the early 20th century until the 1960s was due to an increase in the prevalence of coronary atherosclerosis with resultant coronary heart disease as documented by autopsy studies. This increase was associated with an increase in smoking and dietary changes leading to an increase in serum cholesterol levels. In addition, the ability to diagnose acute myocardial infarction with the aid of the ECG increased the recognition of coronary heart disease prior to death The dramatic decrease in coronary heart disease deaths after the mid1960s is best explained by the decreased incidence, and case fatality rate, of acute myocardial infarction and a decrease in out of hospital sudden coronary heart disease deaths. These decreases are very explained by a decrease in coronary atherosclerosis due to primary prevention, and a decrease in the progression of non-obstructive coronary atherosclerosis to obstructive coronary heart disease due to efforts of primary and secondary prevention. In addition, more effective treatment of patients hospitalized with acute myocardial infarction has led to a dramatic decrease in deaths due to acute myocardial infarction. It is very likely that the 20th century was the only century in which heart disease was the most common cause of death in America.
Authors:
J E Dalen; J S Alpert; R J Goldberg; R S Weinstein
Publication Detail:
Type:  REVIEW     Date:  2014-5-5
Journal Detail:
Title:  The American journal of medicine     Volume:  -     ISSN:  1555-7162     ISO Abbreviation:  Am. J. Med.     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A cost sensitive inpatient bed reservation approach to reduce emergency department boarding times.
Next Document:  Risk of hyponatremia with diuretics: chlorthalidone versus hydrochlorothiazide.