| Epicardial radiofrequency ablation on a beating heart: an experimental study. | |
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MedLine Citation:
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PMID: 15788964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The effect of epicardial radiofrequency ablation (RFA) during normal heart beating was experimentally studied in order to establish safe and effective procedures for RFA. METHODS: Seven pigs weighing approximately 30 to 50 kg were used in this study. Fifty-one epicardial RFA lesions were created on both atria using a Cobra Cooled probe with continuous internal irrigation of a saline solution. The ablation temperature was fixed at 80 degrees C and the duration of the RFA in each case was 20, 30, 60 and 120 seconds. RESULTS: There was significant positive correlation between the right and left atria in wall thickness. Transmural coagulation was obtained in 69% of the total specimens, which decreased according to the increase of wall thickness especially over 3 mm. Transmural coagulation was seen in 64% of the specimens after RFA of less than 30 seconds, and 86% after ablation of >or=60 seconds. Occurence of 90% or deeper coagulation was higher in the right atrium than in the left one (97% vs. 78%). Right atrial rupture occurred in a region of 1 mm in thickness after ablation of 60 seconds. CONCLUSION: Further technical improvements associated with new instruments are indispensable to complete epicardial RFA procedures on a beating heart. |
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Authors:
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Susumu Ishikawa; Shigeru Oki; Masato Muraoka; Kiyohiro Oshima; Kenji Kashiwabara; Yasuo Morishita |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia Volume: 11 ISSN: 1341-1098 ISO Abbreviation: Ann Thorac Cardiovasc Surg Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-03-24 Completed Date: 2005-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9703158 Medline TA: Ann Thorac Cardiovasc Surg Country: Japan |
Other Details:
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Languages: eng Pagination: 21-4 Citation Subset: IM |
Affiliation:
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Second Department of Surgery, Gunma University Graduate School of Medicine, Gunma, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Catheter Ablation / methods* Heart Atria / pathology, physiopathology, surgery Myocardial Contraction / physiology Pericardium / pathology, physiopathology, surgery* Saline Solution, Hypertonic / administration & dosage Swine Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Saline Solution, Hypertonic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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