Document Detail


Epicardial adipose tissue increased in patients with newly diagnosed subclinical hypothyroidism.
MedLine Citation:
PMID:  22889743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate whether or not patients with subclinical hypothyroidism (SH) have increased epicardial adipose tissue (EAT).
SUBJECTS AND METHODS: Sixty-one patients with newly diagnosed SH and without any known cardiovascular disease were enrolled. Twenty-four subjects matched for age, gender and body mass index without any thyroid dysfunctions were included as a control group. The EAT was measured by echocardiography and thyroid functions were assessed by routine blood examination.
RESULTS: Patients with SH had higher EAT values than control subjects (3.6 ± 0.9 vs. 2.8 ± 1.4, p = 0.005). Also, SH patients with thyroid-stimulating hormone (TSH) ≥10 mU/l had higher EAT than those with SH with TSH <10 mU/l and control subjects (p = 0.013). In addition, while there was significant correlation between EAT and TSH (r = 0.31, p = 0.014) in patients with SH, there was no significant relation between EAT and TSH in normal subjects (r = 0.09, p = 0.64).
CONCLUSIONS: There was a higher level of EAT in patients with SH compared with normal subjects and a significant correlation between EAT and TSH was found.
Authors:
Levent Korkmaz; Sinan Sahin; Ali Riza Akyuz; Murat Ziyrek; Inan Anaforoglu; Mustafa Kose; Hakan Erkan; Mustafa Tarık Ağaç; Zeydin Acar
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Publication Detail:
Type:  Journal Article     Date:  2012-08-09
Journal Detail:
Title:  Medical principles and practice : international journal of the Kuwait University, Health Science Centre     Volume:  22     ISSN:  1423-0151     ISO Abbreviation:  Med Princ Pract     Publication Date:  2013  
Date Detail:
Created Date:  2012-12-21     Completed Date:  2013-06-04     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8901334     Medline TA:  Med Princ Pract     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  42-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / physiopathology*
Adult
Echocardiography
Female
Humans
Hypothyroidism / complications*
Male
Middle Aged
Pericardium*
Thyroid Function Tests
Comments/Corrections
Comment In:
Med Princ Pract. 2013;22:603   [PMID:  23571477 ]
Med Princ Pract. 2013;22:604   [PMID:  24350364 ]
Med Princ Pract. 2013;22:605   [PMID:  23970177 ]
Med Princ Pract. 2013;22:605   [PMID:  24350366 ]

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