| Epicardial Adipose Tissue Increased in Patients with Newly Diagnosed Subclinical Hypothyroidism. | |
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MedLine Citation:
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PMID: 22889743 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: To investigate whether or not patients with subclinical hypothyroidism (SH) have increased epicardial adipose tissue (EAT). Subjects and Methods: Sixty-one patients with newly diagnosed SH and without any known cardiovascular disease were enrolled. Twenty-four subjects matched for age, gender and body mass index without any thyroid dysfunctions were included as a control group. The EAT was measured by echocardiography and thyroid functions were assessed by routine blood examination. Results: Patients with SH had higher EAT values than control subjects (3.6 ± 0.9 vs. 2.8 ± 1.4, p = 0.005). Also, SH patients with thyroid-stimulating hormone (TSH) ≥10 mU/l had higher EAT than those with SH with TSH <10 mU/l and control subjects (p = 0.013). In addition, while there was significant correlation between EAT and TSH (r = 0.31, p = 0.014) in patients with SH, there was no significant relation between EAT and TSH in normal subjects (r = 0.09, p = 0.64). Conclusions: There was a higher level of EAT in patients with SH compared with normal subjects and a significant correlation between EAT and TSH was found. |
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Authors:
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Levent Korkmaz; Sinan Sahin; Ali Riza Akyuz; Murat Ziyrek; Inan Anaforoglu; Mustafa Kose; Hakan Erkan; Mustafa Tarık Ağaç; Zeydin Acar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-09 |
Journal Detail:
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Title: Medical principles and practice : international journal of the Kuwait University, Health Science Centre Volume: - ISSN: 1423-0151 ISO Abbreviation: Med Princ Pract Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8901334 Medline TA: Med Princ Pract Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
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Department of Cardiology, Ahi Evren Thoracic and Cardiovascular Surgery Training and Research Hospital, Trabzon, Turkey. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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