Document Detail

Ependymoblastoma in an adult: a diagnostic challenge on cytology.
MedLine Citation:
PMID:  22674109     Owner:  NLM     Status:  MEDLINE    
Ependymoblastoma is a rare, highly malignant brain tumour considered by most to be a subtype of primitive neuroectodermal tumour manifesting in young children. The authors present an unusual case of ependymoblastoma occurring in an 18-year-old female, one of the oldest patients reported with this tumour. The crush smears were highly cellular comprising singly scattered small, round immature cells with fine granular chromatin. The paraffin sections showed a tumour composed of uniform, small-sized, primitive cells forming well defined multi-layered rosettes with prominent mitoses. The tumour cells exhibited diffuse Vimentin and focal glial fibrillary acidic protein reactivity. A few cells showed S-100 reactivity. The patient underwent radiotherapy following complete tumour debulking but, succumbed to the disease within 2 months of diagnosis.
Sonal Amit; Priyanka Chand; Chayanika Pantola; Asha Agarwal
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-11-08
Journal Detail:
Title:  BMJ case reports     Volume:  2011     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2011  
Date Detail:
Created Date:  2012-06-07     Completed Date:  2013-08-26     Revised Date:  2013-12-05    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
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MeSH Terms
Brain Neoplasms / pathology*
Neuroectodermal Tumors, Primitive / pathology*

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