Document Detail

Eosionophilic pseudotumor of the liver due to Ascaris suum infection.
MedLine Citation:
PMID:  12191679     Owner:  NLM     Status:  Publisher    
A case of eosinophilic pseudotumor of the liver due to Ascaris (A) suum is described in a 34-year-old-man with a high serum level of immunoglobulin E and hypereosinophilia ascribed to a history of atopic dermatitis since childhood. Multiple hepatic hypoechoic nodules detected by ultrasound were confirmed as low-density nodules on computed tomography (CT), and as low and high signal intensity lesions on T1-and T2-weighted magnetic resonance imaging (MRI), respectively. CT during arteriography (CTA) and arterial portography revealed multiple nodules with ring-shaped enhancement and perfusion defect, respectively. Biopsied liver tissue specimens did not contain tumor cells or atypical cells; instead, they showed marked infiltration of eosinophils with necrosis and Charcot-Leyden crystals in the portal tracts and hepatic sinusoides, suggesting parasitic infection, although neither larvae nor eggs were detected. The diagnosis of visceral larva migrans (VLM) due to A. suum was based on immunoserological tests. The patient was a habitual consumer of raw bovine liver, which may explain the A. suum infection. After drug therapy with albendazole, the hypoechoic nodules disappeared. Differential diagnoses and the possible transfection route of A. suum are discussed.
Soo Kim; Yoko Maekawa; Toshiyuki Matsuoka; Susumu Imoto; Kenji Ando; Keiji Mita; Haeng Kim; Taisuke Nakajima; Kwansong Ku; Toshihiro Koterazawa; Katsumi Fukuda; Yoshihiko Yano; Miyuki Nakaji; Masatoshi Kudo; Ke Kim; Midori Hirai; Yoshitake Hayashi
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Publication Detail:
Journal Detail:
Title:  Hepatology research : the official journal of the Japan Society of Hepatology     Volume:  23     ISSN:  -     ISO Abbreviation:  Hepatol. Res.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-Aug-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9711801     Medline TA:  Hepatol Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  306     Citation Subset:  -    
Department of Gastroenterology, Kobe Asahi Hospital, 3-5-25 Bouoji-cho, Nagata-ku, 653-0801, Kobe, Japan
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