| Eosinophils: changing perspectives in health and disease. | |
| | |
MedLine Citation:
|
PMID: 23154224 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector cells. Recent studies have profoundly altered this simplistic view of eosinophils and their function. New insights into the molecular pathways that control the development, trafficking and degranulation of eosinophils have improved our understanding of the immunomodulatory functions of these cells and their roles in promoting homeostasis. Likewise, recent developments have generated a more sophisticated view of how eosinophils contribute to the pathogenesis of different diseases, including asthma and primary hypereosinophilic syndromes, and have also provided us with a more complete appreciation of the activities of these cells during parasitic infection. |
| | |
Authors:
|
Helene F Rosenberg; Kimberly D Dyer; Paul S Foster |
Related Documents
:
|
17362684 - Cardiovascular mri for stem cell therapy. 23617754 - Plasmacytoid dendritic cells: no longer an enigma and now key to transplant tolerance? 23220114 - A novel in vitro model system for smooth muscle differentiation from human embryonic st... 22998814 - Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integri... 160614 - Lymphocyte subpopulations in man: b-cell stimulation induced by pokeweed mitogen and ir... 8701944 - Deficiency of cd34+ c-kit+ and cd34+38- hematopoietic precursors in aplastic anemia aft... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-11-16 |
Journal Detail:
|
Title: Nature reviews. Immunology Volume: - ISSN: 1474-1741 ISO Abbreviation: Nat. Rev. Immunol. Publication Date: 2012 Nov |
Date Detail:
|
Created Date: 2012-11-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101124169 Medline TA: Nat Rev Immunol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Recognition of CD1d-restricted antigens by natural killer T cells.
Next Document: What have we learned about the treatment of type 2 diabetes? The evolving paradigms.