Document Detail


Eosinophils are neither migrated nor activated in the skin lesions of atopic dermatitis in infants.
MedLine Citation:
PMID:  10780793     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eosinophils and eosinophil cationic protein (ECP) were examined in the skin lesions of 10 infants with atopic dermatitis (aged 4 months to 7 years). In all 10 patients, neutrophils and eosinophils were rarely seen in these lesions. Moreover, in the immunohistochemical study, ECP was scarcely detected in any of them. Our results suggest that eosinophils are neither migrated nor activated in the skin in atopic dermatitis in infants.
Authors:
N Kondo; S Shinoda; O Fukutomi; H Agata; T Terada; H Shikano; A M Montaño; H Sakaguchi; M Watanabe; K Komiyama; Y Yokoyama; N Morimoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of investigational allergology & clinical immunology     Volume:  10     ISSN:  1018-9068     ISO Abbreviation:  J Investig Allergol Clin Immunol     Publication Date:    2000 Jan-Feb
Date Detail:
Created Date:  2000-06-26     Completed Date:  2000-06-26     Revised Date:  2013-07-31    
Medline Journal Info:
Nlm Unique ID:  9107858     Medline TA:  J Investig Allergol Clin Immunol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  11-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Gifu University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Blood Proteins / analysis*
Cell Movement / immunology*
Child
Child, Preschool
Dermatitis, Atopic / immunology*,  pathology
Eosinophil Granule Proteins
Eosinophils / immunology*
Female
Humans
Infant
Inflammation Mediators / analysis*
Male
Ribonucleases*
Skin / chemistry,  immunology,  pathology
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Eosinophil Granule Proteins; 0/Inflammation Mediators; EC 3.1.-/Ribonucleases

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