| Eosinophilic renal cell tumours. A study on tumour heterogeneity with special emphasis on oncocytes. | |
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MedLine Citation:
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PMID: 1780705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eosinophilic renal tumour cells are found in oncocytomas, granular cell carcinomas, clear cell carcinomas and in a recently defined entity known as "congeners of oncocytomas". Ultrastructural examination of paraffin embedded tumour tissue representing eosinophilic areas in 40 renal cell tumours was performed in order to characterize the different types of eosinophilic cells. The results showed all tumours diagnosed light microscopically as oncocytomas to be composed of cells containing abundant mitochondria. Similar cells were, however, also found in one case of a clear cell carcinoma and in one case diagnosed light microscopically as a "congener". Oncocytes may therefore be found as part of non-oncocytomas and there seems to be a gradual transition from oncocytes to other eosinophilic cells of renal cell carcinomas. Preoperative subclassification of renal cell tumours based on small biopsy specimens is thus of limited value. |
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Authors:
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U Engel; T Horn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of urology and nephrology Volume: 25 ISSN: 0036-5599 ISO Abbreviation: Scand. J. Urol. Nephrol. Publication Date: 1991 |
Date Detail:
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Created Date: 1992-03-12 Completed Date: 1992-03-12 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0114501 Medline TA: Scand J Urol Nephrol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 297-301 Citation Subset: IM |
Affiliation:
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Department of Pathology, Bispebjerg Hospital, University of Copenhagen, Denmark. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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pathology Eosinophils / pathology* Granular Cell Tumor / pathology Humans Kidney Neoplasms / pathology* |
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