Document Detail


Eosinophilic myocarditis in an adolescent: a case report and review of the literature.
MedLine Citation:
PMID:  22995363     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eosinophilic myocarditis is a rare disease occurring mainly in adulthood. It is generally known to be caused by autoimmune diseases, parasitic infections, hypersensitivity to drugs or substances, and after vaccinations. We describe the case of a 15-year-old adolescent, who presented initially with flu-like symptoms, as well as syncope. Subsequently, catecholaminergic treatment had to be initialised because of cardiac failure. Peripheral eosinophil count was normal at admission and at the time of endomyocardial biopsy. The biopsy, however, proved the diagnosis of eosinophilic myocarditis, but the causative agent remained unclear despite intensive diagnostic work-up. Cardiac magnetic resonance imaging showed signs of acute myocardial oedema and a delayed enhancement in the basal inferolateral segments consistent with acute myocarditis. Under treatment with corticosteroids, angiotensin-converting enzyme inhibitor, and warfarin, we accomplished a rapid and complete recovery of cardiac function and histology. This unique case of eosinophilic myocarditis is rare in childhood. The differential diagnosis and diagnostic pathway is discussed, and a review of the literature and therapeutic options based on the literature is performed.
Authors:
Ilhan Aslan; Marcus Fischer; Kai T Laser; Nikolaus A Haas
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2012-09-21
Journal Detail:
Title:  Cardiology in the young     Volume:  23     ISSN:  1467-1107     ISO Abbreviation:  Cardiol Young     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-06-11     Completed Date:  2014-02-10     Revised Date:  2014-02-18    
Medline Journal Info:
Nlm Unique ID:  9200019     Medline TA:  Cardiol Young     Country:  England    
Other Details:
Languages:  eng     Pagination:  277-83     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anti-Inflammatory Agents / therapeutic use
Biopsy
Edema / pathology
Eosinophilia / complications,  diagnosis*,  drug therapy
Heart Failure / etiology
Humans
Male
Myocarditis / complications,  diagnosis*,  drug therapy
Myocardium / pathology*
Prednisolone / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 9PHQ9Y1OLM/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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