Document Detail

Eosinophilic granuloma of the ischium in an infant.
MedLine Citation:
PMID:  18391809     Owner:  NLM     Status:  MEDLINE    
This report presents an infant with a solitary eosinophilic granuloma (EG) in an unusual localization at an unusual age treated solely by vinblastine. A solitary EG of the right ischium was detected in a 17-month-old infant as confirmed by a computerized tomography-guided biopsy. He was treated with vinblastine, which was given 6 mg/m per week for a total of six doses. A complete cure was obtained as confirmed by a disease-free follow-up period of 5 years. Chemotherapy is an effective treatment option for a solitary EG in young children considering the risk of dissemination. Moreover, if the disease involves an area where surgery is considered difficult and morbid, or if it involves soft tissues, single-drug chemotherapy can be considered for treatment.
Mehmet Oguz Durakbasa; Nedret Okan; Ozkan Kose; Mucahit Gorgec
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric orthopedics. Part B     Volume:  17     ISSN:  1060-152X     ISO Abbreviation:  J Pediatr Orthop B     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-08     Completed Date:  2008-07-24     Revised Date:  2012-09-17    
Medline Journal Info:
Nlm Unique ID:  9300904     Medline TA:  J Pediatr Orthop B     Country:  United States    
Other Details:
Languages:  eng     Pagination:  125-7     Citation Subset:  IM    
Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey.
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MeSH Terms
Eosinophilic Granuloma* / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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