Document Detail

Eosinophilic gastroenteritis.
MedLine Citation:
PMID:  8578348     Owner:  NLM     Status:  MEDLINE    
Eosinophilic gastroenteritis is a rare condition of unknown etiology characterized by peripheral eosinophilia, eosinophilic infiltration of the gastrointestinal tract, and gastrointestinal symptomatology. Eosinophilic gastroenteritis is generally classified according to the layer of gastrointestinal tract involved. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea, weight loss, anemia, protein-losing enteropathy, and intestinal perforation. Patients with muscular layer disease generally have obstructive symptoms. Subserosal eosinophilic infiltration may result in development of eosinophilic ascites. Patients with mild and sporadic symptoms can be managed with reassurance and expectant observation. Patients with disabling symptoms can be effectively treated with corticosteroids after other systemic disorders associated with peripheral eosinophilia have been excluded. Occasionally, sodium cromolyn, ketotifen, and/or elimination diets have been shown to be effective in the management of patients who have a significant history of allergic disorder. Surgical intervention may be required in patients with obstructive complications or refractory disease.
M Lee; W G Hodges; T L Huggins; E L Lee
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  89     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-03-14     Completed Date:  1996-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  189-94     Citation Subset:  AIM; IM    
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.
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MeSH Terms
Abdominal Pain / physiopathology
Anemia / physiopathology
Anti-Allergic Agents / therapeutic use
Cromolyn Sodium / therapeutic use
Diarrhea / physiopathology
Eosinophilia / classification,  pathology*,  physiopathology
Food Habits
Gastric Mucosa / pathology
Gastroenteritis / classification,  pathology*,  physiopathology
Glucocorticoids / therapeutic use
Intestinal Mucosa / pathology
Intestinal Obstruction / physiopathology
Intestinal Perforation / physiopathology
Ketotifen / therapeutic use
Middle Aged
Nausea / physiopathology
Protein-Losing Enteropathies / physiopathology
Vomiting / physiopathology
Weight Loss
Reg. No./Substance:
0/Anti-Allergic Agents; 0/Glucocorticoids; 15826-37-6/Cromolyn Sodium; 34580-13-7/Ketotifen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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