Document Detail

Eosinophilic fasciitis associated with L-tryptophan ingestion.
MedLine Citation:
PMID:  1435477     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To present the first case of eosinophilic fasciitis associated with L-tryptophan ingestion. CLINICAL FEATURES: A 23-year-old Australian man developed myalgia and weakness, and later the clinical features of eosinophilic fasciitis, while taking L-tryptophan. INTERVENTION AND OUTCOME: The amino acid supplementation was discontinued and he was treated with prednisone (30 mg/day) for six weeks with significant improvement. CONCLUSION: In sclerodermatous skin diseases, such as eosinophilic fasciitis, the possibility of ingestion of tryptophan-containing products should be considered.
I Grigoris; W de Launey; A P Jevtic
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  157     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-12-10     Completed Date:  1992-12-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  329-30     Citation Subset:  IM    
Skin and Cancer Foundation, Westmead, NSW.
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MeSH Terms
Eosinophilia / chemically induced*,  drug therapy,  pathology
Fasciitis / chemically induced*,  drug therapy,  pathology
Prednisone / therapeutic use
Tryptophan / adverse effects*
Reg. No./Substance:
53-03-2/Prednisone; 73-22-3/Tryptophan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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