Document Detail

Eosinophilic esophagitis.
MedLine Citation:
PMID:  16606552     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Esophagitis is an increasingly diagnosed disease. Patients with gastroesophagic reflux, dysphagia, vomiting or abdominal pain, with a torpid response to the treatment, could be suffering from it. MATERIAL AND METHODS: A 37 year-old male patient with background of gastroesophagic reflux and dysphagia for solids since 2002, self-limited diarrhea episodes and intolerance to alcoholic drinks due to epigastric pain. Skin prick tests, specific IgE, histamine release test and basophil activation test were carried out. RESULTS: Skin prick test to the usual allergens with negative result; prick-prick tests to egg white and yolk, milk and apple with positive result to egg white; total serum IgE within normal levels, specific IgE to egg white with positive result; histamine release test (HRT) and basophil activation test (BAT) with positive result to egg white and yolk. CONCLUSION: The patient was diagnosed eosinophilic esophagitis. The commercial food extracts have a great variability in their allergenic composition, which could result in false negative results in the prick test. Prick-prick with the natural food is a more sensitive technique than prick in the diagnosis of food allergy. There are other useful in vitro techniques, apart from specific IgE, in the diagnosis of food allergy. In our case, an exclusion diet of the involved food was more effective than other treatments for remission of the symptoms.
Judith Antón Remírez; Rosario Escudero; Oscar Cáceres; Margarita Fernández-Benítez
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Allergologia et immunopathologia     Volume:  34     ISSN:  0301-0546     ISO Abbreviation:  Allergol Immunopathol (Madr)     Publication Date:    2006 Mar-Apr
Date Detail:
Created Date:  2006-04-11     Completed Date:  2006-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370073     Medline TA:  Allergol Immunopathol (Madr)     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  79-81     Citation Subset:  IM    
Department of Allergology and Clinical Immunology, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain.
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MeSH Terms
Anti-Allergic Agents / therapeutic use
Basophil Degranulation Test
Combined Modality Therapy
Conjunctivitis, Allergic / complications
Deglutition Disorders / etiology
Egg White / adverse effects
Egg Yolk / adverse effects
Eosinophilia / diagnosis*,  diet therapy,  etiology
Esophagitis / diagnosis*,  diet therapy,  etiology
False Negative Reactions
Food Hypersensitivity / complications*,  diet therapy,  drug therapy
Gastroesophageal Reflux / complications
Immunoglobulin E / immunology
Pollen / adverse effects
Pyroglyphidae / immunology
Rhinitis, Allergic, Seasonal / complications
Skin Tests
Reg. No./Substance:
0/Anti-Allergic Agents; 37341-29-0/Immunoglobulin E

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