Document Detail


Eosinophilic esophagitis: which role for food and inhalant allergens?
MedLine Citation:
PMID:  23130328     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Eosinophilic esophagitis is a chronic inflammatory disease of the esophagus, immune/antigens mediated, whose incidence is increasing both in adults and pediatric population. It is clinically characterised by symptoms related to esophageal dysfunction and associated with eosinophil-predominant esophageal inflammation. The role of atopy has been clearly demonstrated both in epidemiological and experimental studies and has important implications for diagnosis and therapy. In fact, many evidences show that food and inhalant allergens represent the most important factors involved in the progress of the disease. Several studies have reported that, in a range between 50 and 80%, patients with eosinophilic esophagitis have a prior history of atopy, and for them, the presence of allergic rhinitis, asthma or atopic dermatitis is frequent. Skin tests are able to identify in most patients the allergens involved, allowing a correct dietary approach in order to achieve the remission of symptoms and the biopsy normalization.
Authors:
Erminia Ridolo; Marcello Montagni; Elisa Olivieri; Anthi Rogkakou; Gian Luigi De' Angelis; Giorgio Walter Canonica
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Publication Detail:
Type:  Journal Article     Date:  2012-10-31
Journal Detail:
Title:  Asia Pacific allergy     Volume:  2     ISSN:  2233-8268     ISO Abbreviation:  Asia Pac Allergy     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-11-06     Completed Date:  2012-11-27     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101561954     Medline TA:  Asia Pac Allergy     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  237-41     Citation Subset:  -    
Affiliation:
Department of Clinical and Experimental Medicine, University of Parma, Parma 43100, Italy.
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