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Eosinophilic esophagitis investigated by upper gastrointestinal endoscopy in Japanese patients.
MedLine Citation:
PMID:  21750884     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: The prevalence of eosinophilic esophagitis (EE) is increasing rapidly in Western countries. Several case series of EE have also been reported in Japan. However, the prevalence of EE in Japanese patients as investigated by upper gastrointestinal endoscopy is unknown. Therefore, we carried out a prospective multicenter study to address this issue. METHODS: From July to December 2010, 23,346 patients who had undergone routine upper gastrointestinal endoscopy in 17 institutions were enrolled. In patients with symptoms suggesting EE, such as dysphasia, food impaction, and heartburn, and/or in patients in whom endoscopic findings suggested pathology, esophageal biopsy samples were collected, and the numbers of eosinophils in the squamous epithelium were counted. RESULTS: During the study period of 6 months, 4 patients were endoscopically and histologically diagnosed with EE. The prevalence of EE was calculated to be 17.1/100,000. CONCLUSION: The prevalence of EE in Japanese patients by upper gastrointestinal endoscopy has now been documented.
Authors:
Hirofumi Fujishiro; Yuji Amano; Yoshinori Kushiyama; Shunji Ishihara; Yoshikazu Kinoshita
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-13
Journal Detail:
Title:  Journal of gastroenterology     Volume:  -     ISSN:  1435-5922     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Endoscopy, Shimane Prefectural Central Hospital, Izumo, Japan.
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