Document Detail

Eosinophilia, myositis, and myasthenia gravis associated with a thymoma.
MedLine Citation:
PMID:  16506154     Owner:  NLM     Status:  MEDLINE    
Hypereosinophilia has been associated with a wide variety of systemic disorders, including myositis. Myositis develops in a minority of patients with myasthenia gravis associated with a thymoma. We present a patient who developed a life-threatening myopathy in which testing demonstrated the concurrence of hypereosinophilia, myositis, and myasthenia gravis associated with thymoma. Thymoma-associated T-cell abnormalities may well have contributed to this rare association. This case underscores the need to reevaluate constantly the presumed cause of clinical complaints, as more than one cause may be present.
Irit Avni; Yehonatan Sharabi; Menachem Sadeh; Aron S Buchman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Muscle & nerve     Volume:  34     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-21     Completed Date:  2006-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  United States    
Other Details:
Languages:  eng     Pagination:  242-5     Citation Subset:  IM    
Internal Medicine D, Sheba Medical Center, Tel Hashomer, 52621, Israel.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Blood Cell Count
Cholinesterase Inhibitors / therapeutic use
Eosinophilia / complications*,  pathology
Eye Movements
Muscle, Skeletal / pathology
Myasthenia Gravis / complications*,  drug therapy,  pathology
Myositis / complications*,  diagnosis,  drug therapy,  pathology
Neural Conduction
Neurologic Examination
Peritonitis / etiology
Prednisone / therapeutic use
Pyridostigmine Bromide / therapeutic use
Thymoma / complications*,  pathology
Thymus Neoplasms / complications*,  pathology
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Cholinesterase Inhibitors; 101-26-8/Pyridostigmine Bromide; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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