Document Detail

Eosinophilia in newborn infants.
MedLine Citation:
PMID:  7981553     Owner:  NLM     Status:  MEDLINE    
To evaluate the clinical significance of eosinophilia in newborn infants, 261 admissions to the neonatal unit over a 12-month period were studied retrospectively; 33 babies with eosinophilia (> 1.0 x 10(9)/l) were studied. Clinical and laboratory data for the first month of life were compared, where available, between gestational age-matched pairs with and without eosinophilia. Of the 33 babies with eosinophilia, 23 were > 26 weeks' gestation and all had age-matched controls; 10 were < or = 26 weeks' gestation but had no appropriate gestational age-matched controls. Babies > 26 weeks' gestation with eosinophilia had a significantly higher number of septic episodes than controls: 20 of 23 versus 4 of 23. All 10 babies < or = 26 weeks' gestation with eosinophilia developed sepsis. Infections with gram-negative organisms and necrotizing enterocolitis occurred only in babies who developed eosinophilia. In 5 babies no cause for the eosinophilia was found. In conclusion, eosinophilia in the newborn is usually explainable and is most often associated with infection.
L Patel; B Garvey; S Arnon; I A Roberts
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  83     ISSN:  0803-5253     ISO Abbreviation:  Acta Paediatr.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-05     Completed Date:  1995-01-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  797-801     Citation Subset:  IM    
Department of Neonatal Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
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MeSH Terms
Bacterial Infections / complications*
Blood Cell Count
Bronchoalveolar Lavage Fluid / cytology
Enterocolitis, Pseudomembranous / complications
Eosinophilia / blood,  etiology*
Gestational Age
Infant, Newborn
Infant, Premature
Respiration, Artificial
Retrospective Studies

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