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Eosinophil-induced chronic hepatitis.
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MedLine Citation:
PMID:  9610627     Owner:  NLM     Status:  MEDLINE    
Chronic hepatitis associated with hypereosinophilia has been very rarely reported worldwide. A 7-month-old male infant presented with a high fever, cough, non-projectile vomiting and hepatomegaly. The eosinophil count of the peripheral blood increased up to 21,500/mm3 (49% of WBC). The infant had a history of frequent contact with a neighbor keeping a pigsty. The pathologic examinations of the liver showed severe porto-periportal necroinflammation with marked eosinophilic infiltration, giant cell transformation and ballooning degeneration of hepatocytes, and degranulation of the eosinophils. Bone marrow showed increased eosinophils and decreased myeloid series. Pericardial effusion and bilateral pulmonary consolidation were noted. Corticosteroid aggravated the clinical symptoms of the infant. Anthelmintic treatment significantly normalized the eosinophil count and liver function tests, but cardiopulmonary manifestations continued.
Y J Kim; J H Jeon; N S Kim; J S Ryu; E K Hong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of Korean medical science     Volume:  13     ISSN:  1011-8934     ISO Abbreviation:  J. Korean Med. Sci.     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-08-10     Completed Date:  1998-08-10     Revised Date:  2011-03-16    
Medline Journal Info:
Nlm Unique ID:  8703518     Medline TA:  J Korean Med Sci     Country:  KOREA    
Other Details:
Languages:  eng     Pagination:  219-22     Citation Subset:  IM    
Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea.
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MeSH Terms
Eosinophils / immunology*
Hepatitis, Chronic / immunology*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Korean Med Sci
Journal ID (pmc): jkms
ISSN: 1011-8934
ISSN: 1598-6357
Publisher: Korean Academy of Medical Sciences
Article Information
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Print publication date: Month: 4 Year: 1998
Volume: 13 Issue: 2
First Page: 219 Last Page: 222
ID: 3054484
PubMed Id: 9610627

Eosinophil-induced chronic hepatitis.
Y. J. Kim
J. H. Jeon
N. S. Kim
J. S. Ryu
E. K. Hong
Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea.

Article Categories:
  • Research Article

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