| Enzyme profile of exudate leukocytes from diabetic rabbits | |
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MedLine Citation:
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PMID: 516996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In leukocytes of exudate from diabetic rabbits, the activities of hexokinase, phosphoglucomutase and glucose-6-phosphate dehydrogenase are increased, and a tendency of adenylate kinase activity to decline is observable. The activities of UDP-pyrophosphatase, UDP-glycogentransferase, 6-phosphogluconate dehydrogenase and glutahione reductase in the exudate erythrocytes in diabetes are not essentially altered. The decrease of the key enzymes of glycolysis and pentose phosphate cycle, providing the leukocytes with energy and metabolites, reduces the functional activity of leukocytes from exudate in diabetes. |
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Authors:
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S A Shestakova |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Acta biologica et medica Germanica Volume: 38 ISSN: 0001-5318 ISO Abbreviation: Acta Biol. Med. Ger. Publication Date: 1979 |
Date Detail:
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Created Date: 1980-02-15 Completed Date: 1980-02-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370276 Medline TA: Acta Biol Med Ger Country: GERMANY, EAST |
Other Details:
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Languages: rus Pagination: 47-51 Citation Subset: IM |
Vernacular Title:
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Enzimaticheskii prophil leukotsitov eksudata pri diabete. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenylate Kinase
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blood Animals Diabetes Mellitus, Experimental / enzymology* Erythrocytes / enzymology Glucosephosphate Dehydrogenase / blood Glucosyltransferases / blood Glutathione Reductase / blood Hexokinase / blood Leukocytes / enzymology* Phosphoglucomutase / blood Phosphogluconate Dehydrogenase / blood Pyrophosphatases / blood Rabbits |
| Chemical | |
Reg. No./Substance:
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EC 1.1.1.43/Phosphogluconate Dehydrogenase; EC 1.1.1.49/Glucosephosphate Dehydrogenase; EC 1.8.1.7/Glutathione Reductase; EC 2.4.1.-/Glucosyltransferases; EC 2.7.1.1/Hexokinase; EC 2.7.4.3/Adenylate Kinase; EC 3.6.1.-/Pyrophosphatases; EC 5.4.2.2/Phosphoglucomutase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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