Document Detail


Enzyme histochemical and ultrastructural studies in human adrenal glands of normal and anencephalic fetuses.
MedLine Citation:
PMID:  6535306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to confirm the functional status of adrenal gland in human anencephalic fetuses, an enzyme histochemical and ultrastructural approach was used to study the adrenocortical cells of normal and anencephalic human fetuses. In the adrenal gland of the anencephalic fetuses (32nd, 34th and 36th week of gestation), enzyme histochemical activities of alkaline phosphatase and acid phosphatase was weaker than those in normal human fetuses (20th and 26th week of gestation). Ultrastructurally, a large number of lipid droplets, rough endoplasmic reticulum, tubular or vesicular profiles of smooth endoplasmic reticulum and mitochondria with poorly developed cristae were noted in the cytoplasm. In addition, Golgi complexes and microvilli were very poorly developed. Based on these findings, functional aspects of the adrenal gland in anencephalic fetuses were discussed.
Authors:
M Murakoshi; Y Osamura; K Watanabe; Y Kuroshima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tokai journal of experimental and clinical medicine     Volume:  9     ISSN:  0385-0005     ISO Abbreviation:  Tokai J. Exp. Clin. Med.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1985-07-11     Completed Date:  1985-07-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704186     Medline TA:  Tokai J Exp Clin Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  119-37     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acid Phosphatase / analysis
Adrenal Glands / enzymology,  ultrastructure*
Alkaline Phosphatase / analysis
Anencephaly / pathology*
Female
Fetus / ultrastructure*
Histocytochemistry
Humans
Pregnancy
Chemical
Reg. No./Substance:
EC 3.1.3.1/Alkaline Phosphatase; EC 3.1.3.2/Acid Phosphatase

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