Document Detail


Enzyme activities in serum after extensive exercise, with special reference to creatine kinase MB.
MedLine Citation:
PMID:  7435265     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is well documented that elevations of serum enzymes used as criteria in establishing the diagnosis of acute myocardial infarction (AMI) often show a pattern of AMI after physical exercise without other clinical signs of myocardial damage. Since a clinical condition resembling AMI sometimes appears after strenuous physical exercise, this study was designed to show if the new, almost heart-specific, isoenzyme creatine kinase MB (CK-MB) would solve the diagnostic problems. Ten well trained volunteers took part in a 26 km jogging race. None of them had any cardiovascular symptoms, but the 'old' cardiac enzymes rose in some of them above the discriminatory levels, whereas CK-MB was below these levels in all cases. It is concluded that CK-MB determination is a valuable diagnostic tool, also in patients who have recently exercised extensively.
Authors:
P Schnohr; P Grande; C Christiansen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  208     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1980  
Date Detail:
Created Date:  1981-01-29     Completed Date:  1981-01-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  229-31     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aspartate Aminotransferases / blood
Child
Creatine Kinase / blood*
Female
Humans
Isoenzymes
L-Lactate Dehydrogenase / blood
Male
Middle Aged
Physical Exertion*
Time Factors
Chemical
Reg. No./Substance:
0/Isoenzymes; EC 1.1.1.27/L-Lactate Dehydrogenase; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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