Document Detail


Enzymatic phosphatidylation of thiamin, pantothenic acid, and their derivatives.
MedLine Citation:
PMID:  18635914     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Phospholipase D from Streptomyces sp. was found to catalyze the transfer reaction of the dipalmitoylphosphatidyl residue from 1,2-dipalmitoyl-3-sn-phosphatidylcholine to thiamin, pantothenic acid, and their derivatives in a biphasic system. The following phosphatidylated compounds were synthesized: 1,2-dipalmitoyl-3-sn-phosphatidylthiamin, 1,2-dipalmitoyl-3-sn-phosphatidylthiamin propyl disulfide, 1,2-dipalmitoyl-3-sn-phosphatidylthiamin tetrahydrofurfuryl disulfide, 1,2-dipalmitoyl-3-sn-phosphatidylpantothenic acid, and 1,2-dipalmitoyl-3-sn-phosphatidyl-pantothenyl ethyl ether.
Authors:
Naomi Hidaka; Masaaki Takami; Yukio Suzuki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nutritional science and vitaminology     Volume:  54     ISSN:  0301-4800     ISO Abbreviation:  J. Nutr. Sci. Vitaminol.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-07-18     Completed Date:  2008-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0402640     Medline TA:  J Nutr Sci Vitaminol (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  255-61     Citation Subset:  IM    
Affiliation:
Research Institute for Bioresources, Okayama University, Kurashiki, Japan.
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MeSH Terms
Descriptor/Qualifier:
1,2-Dipalmitoylphosphatidylcholine / chemical synthesis
Catalysis
Chromatography, Thin Layer
Molecular Structure
Pantothenic Acid / chemical synthesis*,  chemistry
Phosphatidylcholines / chemical synthesis
Phospholipase D / chemistry*
Thiamine / chemical synthesis*,  chemistry
Time Factors
Chemical
Reg. No./Substance:
0/Phosphatidylcholines; 2644-64-6/1,2-Dipalmitoylphosphatidylcholine; 59-43-8/Thiamine; 79-83-4/Pantothenic Acid; EC 3.1.4.4/Phospholipase D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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