Document Detail


Enzymatic degradation of human skin dermis revealed by fluorescence and reflectance spectroscopy.
MedLine Citation:
PMID:  18575556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dermis is the major source of the fluorescence and light scattering of skin. Tumor-induced degradation of the dermis is expected to change the fluorescence and light scattering properties of skin. To investigate how these fluorescence and light scattering properties are changed, human skin dermis was degraded with enzymes to mimic tumor invasion. The enzymatic erosion process was investigated with fluorescence and reflectance spectroscopy. Dermis degradation by the enzymes resulted in a decrease in fluorescence emission and light scattering in the dermis. Fluorescence anisotropy, however, could not detect the change in the dermis induced by the enzyme treatments.
Authors:
Ye Yuan; Patricia Relue
Related Documents :
22501086 - Acoustic analysis of trill sounds.
12659496 - Effects of uv and visible light on cyanobacteria at the cellular level.
17713846 - Segmented frequency-domain fluorescence lifetime measurements: minimizing the effects o...
21299656 - Cone arrestin confers cone vision of high temporal resolution in zebrafish larvae.
8474846 - The role of depth stratification in the solution of the aperture problem.
6985106 - Local stimulation induces shedding throughout the frog retina.
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Optics express     Volume:  16     ISSN:  1094-4087     ISO Abbreviation:  Opt Express     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-25     Completed Date:  2008-08-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137103     Medline TA:  Opt Express     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9857-68     Citation Subset:  IM    
Affiliation:
Cellular Engineering Laboratory, The University of Toledo, Ohio 43606, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Dermis / chemistry*,  enzymology*
Dermoscopy / methods*
Endopeptidases / chemistry*,  metabolism*
Humans
Microscopy, Fluorescence / methods*
Spectrometry, Fluorescence / methods*
Chemical
Reg. No./Substance:
EC 3.4.-/Endopeptidases; EC 3.4.99.-/dispase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Optical aberrations in a spinning pipe gas lens.
Next Document:  All optical switches based on the coupling of surface plasmon polaritons.