| Environmental exposures and adverse pregnancy outcomes: a review of the science. | |
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MedLine Citation:
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PMID: 18836129 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To better understand the science linking environmental contaminants exposures with adverse pregnancy outcomes, we reviewed the relevant epidemiologic literature. We searched PubMed (primarily 1995-2006) using the key word combinations for select environmental exposures and pregnancy outcomes. Environmental tobacco smoke is a risk factor for reduced birth weight and preterm delivery. Outdoor air pollution is associated with reduced term birth weight and preterm delivery. Suggestive evidence associates pesticides and polychlorinated biphenyls with decreased fetal growth and length of gestation. Stronger evidence, primarily occupational, links certain birth defects with exposure to organic solvents and chlorophenoxy herbicides. Evidence suggests dichlorodiphenyltrichloroethane and bisphenol-A could be associated with pregnancy loss. Exposures in utero can also increase the risk of developmental delays (ie, impaired neurological function), adult chronic illnesses (ie, heart disease, diabetes, cancer), and next generation effects (ie, reduced reproductive capacity). Further research, education, and improved public health policy are needed to reduce potentially adverse exposures. |
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Authors:
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Karen Perry Stillerman; Donald R Mattison; Linda C Giudice; Tracey J Woodruff |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Reproductive sciences (Thousand Oaks, Calif.) Volume: 15 ISSN: 1933-7205 ISO Abbreviation: Reprod Sci Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-10-06 Completed Date: 2009-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101291249 Medline TA: Reprod Sci Country: United States |
Other Details:
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Languages: eng Pagination: 631-50 Citation Subset: IM |
Affiliation:
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Physicians for Social Responsibility. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Environmental Exposure / adverse effects*, prevention & control Female Humans Infant, Newborn Maternal Exposure Occupational Diseases / epidemiology, etiology, prevention & control Pregnancy Pregnancy Complications / epidemiology, etiology, prevention & control Pregnancy Outcome / epidemiology* Prenatal Exposure Delayed Effects / epidemiology*, etiology, prevention & control |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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