Document Detail


Environmental exposure to emissions from petrochemical sites and lung cancer: the lower Mississippi interagency cancer study.
MedLine Citation:
PMID:  20300547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To investigate potential links between environmental exposure to petrochemical plant emissions and lung cancer, a population-based case-control study (LMRICS) was conducted in eleven Louisiana parishes bordering the Mississippi River. Cases and age, gender, and race-matched controls were interviewed regarding potential risk factors. Residential history was geocoded to provide indices of long-term proximity to industrial sites. Cases were more likely to have lived near a petrochemical site. Models adjusted for other risk factors, however, showed small or no association with lung cancer (odds ratio for residence within a half-mile of a site = 1.10, 95% confidence interval 0.58-2.08). While associations were strongest for exposures exceeding 15 years, none approached statistical significance and there was no clear dose-response across exposure duration, distance categories, or when sites were grouped according to carcinogenicity rating of chemical releases. Residential proximity to petrochemical plants along the lower Mississippi thus showed no significant association with lung cancer.
Authors:
Neal Simonsen; Richard Scribner; L Joseph Su; Donna Williams; Brian Luckett; Tong Yang; Elizabeth T H Fontham
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-03-14
Journal Detail:
Title:  Journal of environmental and public health     Volume:  2010     ISSN:  1687-9813     ISO Abbreviation:  J Environ Public Health     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-19     Completed Date:  2012-04-16     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101516361     Medline TA:  J Environ Public Health     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  759645     Citation Subset:  IM    
Affiliation:
School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Air Pollutants / adverse effects*
Carcinogens, Environmental / adverse effects
Case-Control Studies
Environmental Exposure / adverse effects*,  statistics & numerical data
Extraction and Processing Industry*
Female
Humans
Hydrocarbons / adverse effects*
Logistic Models
Louisiana
Lung Neoplasms / chemically induced*,  epidemiology
Male
Middle Aged
Odds Ratio
Petroleum / adverse effects*
Questionnaires
Registries
Residence Characteristics
Risk Factors
Time Factors
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Carcinogens, Environmental; 0/Hydrocarbons; 0/Petroleum
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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