Document Detail


Environmental Risk Assessment of antimicrobials applied in veterinary medicine-A field study and laboratory approach.
MedLine Citation:
PMID:  23274419     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The fate and environmental risk of antimicrobial compounds of different groups of veterinary medicine pharmaceuticals (VMP's) have been compared. The aim was to demonstrate a correlation between the physical and chemical properties of active compounds and their metabolism in target animals, as well as their fate in the environment. In addition, the importance of techniques for manure management and agricultural practice and their influence on the fate of active compounds is discussed. The selected active compounds are shown to be susceptible to at least one environmental factor (sun, water, bacterial or fungal degradation) to which they are exposed during their life cycle, which contributes to its degradation. Degradation under a number of environmental factors has also to be considered as authentic information additional to that observed in the limited conditions in laboratory studies and in Environmental Risk Assessment calculations.
Authors:
Marko Slana; Marija Sollner Dolenc
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-7
Journal Detail:
Title:  Environmental toxicology and pharmacology     Volume:  35     ISSN:  1872-7077     ISO Abbreviation:  Environ. Toxicol. Pharmacol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612020     Medline TA:  Environ Toxicol Pharmacol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  131-141     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
Affiliation:
Krka, d. d., Novo mesto, Šmarješka cesta 6, 8501 Novo mesto, Slovenia.
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