| Envelope amplitude analysis following narrow-band filtering: a technique for ultrasonic tissue characterization. | |
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MedLine Citation:
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PMID: 3306304 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ultrasonic waveforms backscattered from tissue simulating phantoms and from normal and cirrhotic human livers in vivo were digitized to a standard dynamic range prior to envelope detection and determination of envelope amplitude distributions. For 11 individual narrow-band Gaussian-shaped filters of -6 dB bandwidth 200 kHz, and of center frequencies from 2 to 4 MHz, envelope amplitude distributions were plotted and mean values of the values distributions computed. Analysis of data was performed for data from a phantom containing only relatively small graphite scatters (less than 170 mu), and a similar phantom to which glass spheres 0.5 mm in diameter had been added homogeneously. For lower center frequency narrow-band filters, significantly more high-amplitude occurrences were observed for data from the phantom to which glass spheres had been added. Higher center frequency narrow-band filters gave significantly more high-amplitude occurrences for the phantom containing only small scatters. Similar data analysis was performed for in vivo human liver data from ten normal subjects and five patients with known cirrhosis of the liver. For the cirrhotic and normal livers, data analysis using narrow-band filters of relatively low center frequency resulted in more high- amplitude occurrences for cirrhotic, compared to normal liver; the converse was true for narrow-band filtration at relatively high center frequencies. Determination of mean amplitude following narrow-band filtration with a filter centered at 3.4 MHz was found to be quite repeatable for the normal and cirrhotic liver data; analysis of variance showed the measurement was 94.1% a function of the subject examined, and 5.9% related to the data acquisition session.(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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F G Sommer; R A Stern; P J Howes; H Young |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Medical physics Volume: 14 ISSN: 0094-2405 ISO Abbreviation: Med Phys Publication Date: 1987 Jul-Aug |
Date Detail:
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Created Date: 1987-10-07 Completed Date: 1987-10-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0425746 Medline TA: Med Phys Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 627-32 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Liver / anatomy & histology*, pathology Liver Cirrhosis / diagnosis* Reference Values Ultrasonography / methods* |
| Grant Support | |
ID/Acronym/Agency:
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5 K04 CA00960/CA/NCI NIH HHS; 5R01 CA37483/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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