| Entry of viruses through the epithelial barrier: pathogenic trickery. | |
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MedLine Citation:
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PMID: 12511869 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mucosal surfaces--such as the lining of the gut or the reproductive tract--are the main point of entry for viruses into the body. As such, almost all viruses interact with epithelial cells, and make use of the normal epithelial signalling and trafficking pathways of the host cell. In addition to protein receptors, carbohydrate chains of proteoglycans and epithelial-membrane glycosphingolipids have emerged as a new class of receptors for viral attachment to the host cell. |
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Authors:
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Morgane Bomsel; Annette Alfsen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Nature reviews. Molecular cell biology Volume: 4 ISSN: 1471-0072 ISO Abbreviation: Nat. Rev. Mol. Cell Biol. Publication Date: 2003 Jan |
Date Detail:
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Created Date: 2003-01-03 Completed Date: 2003-02-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100962782 Medline TA: Nat Rev Mol Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 57-68 Citation Subset: IM |
Affiliation:
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Laboratory of Mucosal Entry of HIV and Mucosal Immunity, Département de Biologie Cellulaire, Institut Cochin, Centre National de la Recherche Scientifique, INSERM, Université René Descartes, 22 rue Mechain, 75014 Paris, France. bomsel@cochin.inserm.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biological Transport Epithelial Cells / virology* Humans Receptors, Virus / metabolism Signal Transduction Virus Physiological Phenomena* Viruses / pathogenicity* |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Virus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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