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Enterovirus 71-associated hand, foot, and mouth disease, Southern Vietnam, 2011.
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MedLine Citation:
PMID:  23194699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We prospectively studied 3,791 children hospitalized during 2011 during a large outbreak of enterovirus 71-associated hand, foot, and mouth disease in Vietnam. Formal assessment of public health interventions, use of intravenous immunoglobulin and other therapies, and factors predisposing for progression of disease is needed to improve clinical management.
Authors:
Truong Huu Khanh; Saraswathy Sabanathan; Tran Tan Thanh; Le Phan Kim Thoa; Tang Chi Thuong; Vu thi Ty Hang; Jeremy Farrar; Tran Tinh Hien; Nguyen van Vinh Chau; H Rogier van Doorn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Emerging infectious diseases     Volume:  18     ISSN:  1080-6059     ISO Abbreviation:  Emerging Infect. Dis.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-30     Completed Date:  2013-04-26     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  9508155     Medline TA:  Emerg Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2002-5     Citation Subset:  IM    
Affiliation:
Children’s Hospital 1, Ho Chi Minh City, Vietnam.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Disease Outbreaks*
Enterovirus A, Human / classification,  genetics*
Female
Hand, Foot and Mouth Disease / epidemiology*
Humans
Infant
Infant, Newborn
Male
Phylogeny
Vietnam / epidemiology
Viral Proteins / genetics
Grant Support
ID/Acronym/Agency:
089276/Z/09/Z//Wellcome Trust
Chemical
Reg. No./Substance:
0/Viral Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Emerg Infect Dis
Journal ID (iso-abbrev): Emerging Infect. Dis
Journal ID (publisher-id): EID
ISSN: 1080-6040
ISSN: 1080-6059
Publisher: Centers for Disease Control and Prevention
Article Information
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Print publication date: Month: 12 Year: 2012
Volume: 18 Issue: 12
First Page: 2002 Last Page: 2005
PubMed Id: 23194699
ID: 3557876
Publisher Id: 12-0929
DOI: 10.3201/eid1812.120929

Enterovirus 71–associated Hand, Foot, and Mouth Disease, Southern Vietnam, 2011 Alternate Title:EV71-associated HFMD, Vietnam
Truong Huu Khanh
Saraswathy Sabanathan
Tran Tan Thanh
Le Phan Kim Thoa
Tang Chi Thuong
Vu thi Ty Hang
Jeremy Farrar
Tran Tinh Hien
Nguyen van Vinh Chau
H. Rogier van Doorn
Author affiliations: Children’s Hospital 1, Ho Chi Minh City, Vietnam (T.H. Khanh, L.P.K. Thoa, T.C. Thuong);
Oxford University Clinical Research Unit, Oxford, UK (S. Sabanathan, T.T. Thanh, V.t.T. Hang, J. Farrar, T.T. Hien, H.R. van Doorn);
Oxford University (S. Sabanathan, J. Farrar, T.T. Hien, H.R. van Doorn);
Hospital for Tropical Diseases, Ho Chi Minh City (N.v.V. Chau)
Correspondence: Address for correspondence: H. Rogier van Doorn, Oxford University Clinical Research Unit, 764 Vo Van Kiet, Ward 1, District 5, Ho Chi Minh City, Vietnam; email: hrogier@gmail.com

Medscape CME Activity

Medscape, LLC is pleased to provide online continuing medical education (CME) for this journal article, allowing clinicians the opportunity to earn CME credit.

This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is accredited by the ACCME to provide continuing medical education for physicians.

Medscape, LLC designates this Journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test with a 70% minimum passing score and complete the evaluation at www.medscape.org/journal/eid; (4) view/print certificate.

Release date: November 16, 2012; Expiration date: November 16, 2013


Learning Objectives

Upon completion of this activity, participants will be able to:

  • Distinguish the virus type associated with the outbreak of hand, foot, and mouth disease (HFMD) in Vietnam in 2011
  • Analyze how to grade the clinical severity of HFMD
  • Evaluate the clinical presentation of HFMD in the current report
  • Assess the management of HFMD

CME Editor

Karen L. Foster, Technical Writer/Editor, Emerging Infectious Diseases. Disclosure: Karen L. Foster has disclosed no relevant financial relationships.


CME Author

Charles P. Vega, MD, Health Sciences Clinical Professor; Residency Director, Department of Family Medicine, University of California, Irvine. Disclosure: Charles P. Vega, MD, has disclosed no relevant financial relationships.


Authors

Disclosures: Truong Huu Khanh, MD; Saraswathy Sabanathan, MD; Tran Tan Thanh, PhD; Le Phan Kim Thoa, MD; Tang Chi Thuong, MD, PhD; Vu thi Ty Hang, PhD; Jeremy Farrar, BSc, MBBS, FRCP, DPhil; Tran Tinh Hien, MD, PhD; Nguyen van Vinh Chau, MD, PhD; and H. Rogier van Doorn, MD, PhD, have disclosed no relevant financial relationships.


Notes

Suggested citation for this article: Khanh TH, Sabanathan S, Thanh TT, Thoa LPK, Thuong TC, Hang VtT, et al. Enterovirus 71–associated hand, foot, and mouth disease, southern Vietnam, 2011. Emerg Infect Dis [Internet]. 2012 Dec [date cited]. http://dx.doi.org/10.3201/eid1812.120929


Article Categories:
  • CME
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Article Categories:
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Keywords: Keywords: hand foot and mouth disease, Vietnam, enterovirus 71, viruses, children, enterovirus.

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