Document Detail


Enterocyte fatty acid uptake and intestinal fatty acid-binding protein.
MedLine Citation:
PMID:  14748716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reviews our current understanding of the uptake of fatty acids by the enterocytes of the intestine. The micellar solubilization of fatty acids by bile salts and the factors regulating that process are discussed. The mechanism of how micellar solubilization of fatty acids promotes the uptake of fatty acids by enterocytes and their relative importance is reviewed. Additionally, discussion of the various fatty acid transporters located at the brush border membrane of the enterocytes is included. Finally, a summary of our current understanding of the function of fatty-acid-binding proteins inside enterocytes is provided.
Authors:
P Tso; A Nauli; C-M Lo
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Biochemical Society transactions     Volume:  32     ISSN:  0300-5127     ISO Abbreviation:  Biochem. Soc. Trans.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-01-29     Completed Date:  2004-09-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7506897     Medline TA:  Biochem Soc Trans     Country:  England    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  IM    
Affiliation:
Department of Pathology, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH 45267, USA. tsopp@email.uc.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Bile Acids and Salts / metabolism
Carrier Proteins / metabolism*
Enterocytes / metabolism*
Fatty Acid-Binding Proteins
Fatty Acids / metabolism*
Humans
Intestines / metabolism*
Solubility
Chemical
Reg. No./Substance:
0/Bile Acids and Salts; 0/Carrier Proteins; 0/Fatty Acid-Binding Proteins; 0/Fatty Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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