Document Detail

Enterocolic lymphocytic phlebitis: statistical analysis of histology features in viable and ischemic bowel.
MedLine Citation:
PMID:  16959699     Owner:  NLM     Status:  MEDLINE    
Enterocolic lymphocytic phlebitis is a rare cause of segmental ischemic enterocolitis. This artery-sparing transmural vasculitis is classically a circumferential phlebitis with perivenular lymphocyte cuffing and thrombi in the absence of systemic manifestations. Myointimal hyperplasia may represent a chronic phase of enterocolic lymphocytic phlebitis. Subclinical or early stage enterocolic lymphocytic phlebitis is not well delineated. We analyzed 600 submucosal and subserosal veins from both ischemic and intact bowel segments to discern if vascular morphology varied between sites. Crescentic and circumferential lymphocytic phlebitis is more common in viable bowel than in the ischemic segment. A nonsignificant trend was found for increased crescentic morphology between intact bowel remote from the ischemic focus compared with that adjacent to the ischemic focus. Hallmarks of ischemic bowel are necrotizing phlebitis and thrombi formation. Thrombophlebitis morphology is distinctly different in viable and ischemic bowel, changing from the classic lymphocytic to necrotizing lesions respectively.
Shaun A C Medlicott; Kelly A Guggisberg; Jean-Gaston DesCôteaux; Paul Beck
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of surgical pathology     Volume:  14     ISSN:  1066-8969     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-09-08     Completed Date:  2006-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  200-5     Citation Subset:  IM    
Department of Laboratory Medicine, Peter Lougheed Centre, University of Calgary, Calgary, Alberta, Canada.
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MeSH Terms
Cecum / blood supply,  pathology,  surgery
Colitis, Ischemic / etiology,  pathology
Enterocolitis / complications,  pathology*,  surgery
Ileum / blood supply,  pathology,  surgery
Lymphocytes / pathology*
Phlebitis / complications,  pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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