Document Detail

Enteroaggregative Escherichia coli associated with an outbreak of diarrhoea in a neonatal nursery ward.
MedLine Citation:
PMID:  8760945     Owner:  NLM     Status:  MEDLINE    
Over a 9-day period in February 1995, 16 newborn babies (age range 2-11 days) and 3 infants (24, 47 and 180 days of age) in a neonatal nursery ward developed diarrhoea accompanied by pyrexia and weight loss. Known enteropathogens were not detected in their stools but Escherichia coli displaying aggregative adherence to HEp-2 cells (enteroaggregative E. coli) were found in 12 (63%) ill infants and in none of 5 well neonates (P = 0.02). The illness lasted 3-9 days (mean 5.2) in 16 babies, whereas in 3 neonates it showed a protracted course of 18-20 days. The source of infection and the mode of transmission remained unclear. The outbreak isolates manifested properties common in this new group of diarrhoeagenic E. coli: mannose-resistant haemagglutination, haemolysis on blood agar, and clump formation in liquid culture medium. They belonged to the O4 E. coli serogroup and expressed multiple antibiotic resistance.
M Cobeljić; B Miljković-Selimović; D Paunović-Todosijević; Z Velicković; Z Lepsanović; N Zec; D Savić; R Ilić; S Konstantinović; B Jovanović; V Kostić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Epidemiology and infection     Volume:  117     ISSN:  0950-2688     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-09-25     Completed Date:  1996-09-25     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  11-6     Citation Subset:  IM    
Institute of Preventive Medicine, Military Medical Academy, Belgrade, Serbia, Yugoslavia.
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MeSH Terms
Bacterial Adhesion
Diarrhea, Infantile / epidemiology,  microbiology*
Disease Outbreaks*
Escherichia coli / classification*,  isolation & purification
Escherichia coli Infections / epidemiology,  microbiology*
Feces / microbiology
Infant, Newborn
Nurseries, Hospital*
Yugoslavia / epidemiology

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