Document Detail

Enteral and parenteral nutrition in acute pancreatitis.
MedLine Citation:
PMID:  12079265     Owner:  NLM     Status:  MEDLINE    
In the last 5 years naso-enteric feeding has increasingly been used in clinical practice in patients with severe acute pancreatitis. Randomized clinical studies in both mild and severe forms of the disease have demonstrated not only the feasibility but also the safety of this approach. The majority of patients have been fed by variously placed nasojejunal tubes with varied problems in maintaining both location and patency. Most have been surprised to find that it is possible to feed the patients in this way with the potential of improving gut barrier function and immune response, at reduced cost and greater safety than with parenteral nutrition. The current evidence points to nasojejunal feeding being preferable to parenteral feeding, but evidence has yet to be produced to prove beyond reasonable doubt that such feeding is an improvement on conservative management without feeding. Finally, the most recent development has indicated that fine-bore nasogastric feeding may well be a realistic alternative to nasojejunal feeding even in the more severe forms of this disease. A small percentage of patients may still need parenteral nutrition.
Clement W Imrie; C Ross Carter; Colin J McKay
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Best practice & research. Clinical gastroenterology     Volume:  16     ISSN:  1521-6918     ISO Abbreviation:  Best Pract Res Clin Gastroenterol     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-24     Completed Date:  2002-09-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101120605     Medline TA:  Best Pract Res Clin Gastroenterol     Country:  England    
Other Details:
Languages:  eng     Pagination:  391-7     Citation Subset:  IM    
Copyright Information:
Copyright 2002 Elsevier Science Ltd.
Lister Department of Surgery, Royal Infirmary, Glasgow, G31 2ER, Scotland, UK.
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MeSH Terms
Acute Disease
Enteral Nutrition*
Pancreatitis / therapy*
Parenteral Nutrition*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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