Document Detail

Enteral nutrition in treatment of severe acute pancreatitis.
MedLine Citation:
PMID:  14607646     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To observe the role and the timing of EN in the treatment of patients with severe acute pancreatitis (SAP). METHODS: Eleven patients with severe acute pancreatitis underwent systemic nutrition support were studied. EN was given through jejunostomy tube (or Bengmark tube) after a period of PN maintenance. EN started when serum and urine amylase activity returned to normal with regular peristaltic sound, defecation or break wind. The sequence of preparation was as follows: saline glucose-->chemically defined diet-->polymeric diet-->normal diet. RESULTS: In all the patients, none died. The rate of late complications was lower, and the levels of serum albumin and transferritin significantly increased in the post-EN period as compared with the pre-EN period, although the count of lymphocytes was less changed. CONCLUSIONS: Nutritional support should be transformed from PN to EN as early as possible during the treatment of patients with severe acute pancreatitis. EN could not only continue sufficient nutritional support, but also avoid the unfavorable effects of long-time PN, thus reducing complications as well as mortality.
Dun Shi; Cheng-Wu Zhang; Jin-Song Jiang; Zhi-Jie Xie; Shou-Chun Zou
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Hepatobiliary & pancreatic diseases international : HBPD INT     Volume:  1     ISSN:  1499-3872     ISO Abbreviation:  HBPD INT     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2003-11-10     Completed Date:  2004-01-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101151457     Medline TA:  Hepatobiliary Pancreat Dis Int     Country:  China    
Other Details:
Languages:  eng     Pagination:  146-9     Citation Subset:  IM    
Department of General Surgery, Zhejiang Provincial People's Hospital, Hangzhou 310014, China.
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MeSH Terms
Acute Disease
Enteral Nutrition*
Middle Aged
Pancreatitis / diet therapy*
Serum Albumin
Severity of Illness Index
Transferrin / metabolism
Reg. No./Substance:
0/Serum Albumin; 11096-37-0/Transferrin

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