Document Detail

Enhancing health benefits of berries through phenolic antioxidant enrichment: focus on cranberry.
MedLine Citation:
PMID:  15927928     Owner:  NLM     Status:  MEDLINE    
Emerging epidemiological evidence is increasingly pointing to the beneficial effects of fruits and vegetables in managing chronic and infectious diseases. These beneficial effects are now suggested to be due to the constituent phenolic phytochemicals having antioxidant activity. Cranberry like other fruits is also rich in phenolic phytochemicals such as phenolic acids, flavonoids and ellagic acid. Consumption of cranberry has been historically been linked to lower incidences of urinary tract infections and has now been shown to have a capacity to inhibit peptic ulcer-associated bacterium, Helicobacter pylori. Isolated compounds from cranberry have also been shown to reduce the risk of cardiovascular diseases. Recent evidence suggests the ability of phytochemical components in whole foods in being more effective in protectively supporting human health than compared to isolated individual phenolic phytochemicals. This implies that the profile of phenolic phytochemicals determines the functionality of the whole food as a result of synergistic interaction of constituent phenolic phytochemicals. Solid state bioprocessing using food grade fungi common in Asian food cultures as well as cranberry phenolic synergies through the addition of functional biphenyls such as ellagic acid and rosmarinic acid along with processed fruit extracts have helped to advance these concepts. These strategies could be further explored to enrich cranberry and cranberry products with functional phytochemicals and further improve their functionality for enhancing health benefits.
Dhiraj A Vattem; Reza Ghaedian; Kalidas Shetty
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Asia Pacific journal of clinical nutrition     Volume:  14     ISSN:  0964-7058     ISO Abbreviation:  Asia Pac J Clin Nutr     Publication Date:  2005  
Date Detail:
Created Date:  2005-06-01     Completed Date:  2005-09-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440304     Medline TA:  Asia Pac J Clin Nutr     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  120-30     Citation Subset:  IM    
Laboratory of Food Biotechnology, Department of Food Science, University of Massachusetts, Amherst 01003, USA.
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MeSH Terms
Antioxidants / administration & dosage*,  metabolism
Drug Synergism
Health Food*
Phenols / administration & dosage*,  metabolism
Plant Extracts / administration & dosage*
Vaccinium macrocarpon*
Reg. No./Substance:
0/Antioxidants; 0/Phenols; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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