Document Detail

Enhancing cranial nerves and cauda equina: an emerging magnetic resonance imaging pattern in metachromatic leukodystrophy and krabbe disease.
MedLine Citation:
PMID:  20446225     Owner:  NLM     Status:  MEDLINE    
We report on three cases of infantile Krabbe disease and one case of infantile metachromatic leukodystrophy showing magnetic resonance (MR) imaging findings of diffuse and coexistent cranial nerve and cauda equina nerve roots enhancement. Such findings may be simultaneous, or even precede, typical white matter abnormalities and, in the appropriate clinical context, may facilitate an earlier diagnosis. There is a rational for the use of contrast agents and craniospinal MR imaging during the first imaging of children with a history of psychomotor regression and clinical evidence of peripheral nerve involvement to exclude differential diagnoses.
G Morana; R Biancheri; M Dirocco; M Filocamo; M G Marazzi; A Pessagno; A Rossi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-05-05
Journal Detail:
Title:  Neuropediatrics     Volume:  40     ISSN:  1439-1899     ISO Abbreviation:  Neuropediatrics     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-05-06     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8101187     Medline TA:  Neuropediatrics     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  291-4     Citation Subset:  IM    
Copyright Information:
Copyright Georg Thieme Verlag KG Stuttgart New York.
Department of Neuroradiology, G. Gaslini Children's Research Institute, Genoa, Italy.
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MeSH Terms
Cauda Equina / pathology,  physiopathology*
Child, Preschool
Cranial Nerves / pathology,  physiopathology*
Leukodystrophy, Globoid Cell / pathology*,  physiopathology
Leukodystrophy, Metachromatic / pathology*,  physiopathology
Magnetic Resonance Imaging / methods

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