| Enhancing community delivery of tissue plasminogen activator in stroke through community-academic collaborative clinical knowledge translation. | |
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MedLine Citation:
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PMID: 19218023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Improving the clinical outcomes of stroke patients depends on the adoption of proven new therapies throughout the broader medical community. Approximately 1% of stroke patients in community settings are receiving tissue plasminogen activator (tPA) therapy 12 years after US Food and Drug Administration approval. Knowledge translation, the process by which the results of clinical investigations are adopted by clinicians and incorporated into routine practice, is important but often overlooked. This article reviews the history of tPA use in stroke as a case study of a breakdown of knowledge translation in emergency medicine. It reviews knowledge translation concepts and theory and explores practical community-academic collaborative methods based on these tenets to enhance acute stroke care delivery in the community setting. |
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Authors:
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Phillip A Scott |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Emergency medicine clinics of North America Volume: 27 ISSN: 1558-0539 ISO Abbreviation: Emerg. Med. Clin. North Am. Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-16 Completed Date: 2009-03-31 Revised Date: 2011-08-01 |
Medline Journal Info:
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Nlm Unique ID: 8219565 Medline TA: Emerg Med Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 115-36, ix Citation Subset: IM |
Affiliation:
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Department of Emergency Medicine, University of Michigan, Ann Arbor, MI 48106-0381, USA. phlsctt@med.umich.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Competence* Clinical Protocols Crisis Intervention Drug Approval Education, Medical, Continuing Evidence-Based Medicine Feedback, Psychological Humans Internship and Residency Practice Guidelines as Topic Resuscitation / education Self Efficacy Stroke / drug therapy* Tissue Plasminogen Activator / therapeutic use* |
| Grant Support | |
ID/Acronym/Agency:
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R01 NS050372-04/NS/NINDS NIH HHS; R01 NS50372/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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EC 3.4.21.68/Tissue Plasminogen Activator |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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