Document Detail

Enhancement performance of a 64-slice triple rule-out protocol vs 16-slice and 10-slice multidetector CT-angiography protocols for evaluation of aortic and pulmonary vasculature.
MedLine Citation:
PMID:  18043357     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the enhancement of the pulmonary and aortic vasculature between a biphasic injection 64-slice, a single-phase injection 16-slice, and a single-phase injection 10-slice multidetector computed tomographic (CT) angiography (CTA) protocols. METHODS: With institutional review board approval and Health Insurance Portability and Accountability Act compliance, 50 patients (16 men, 34 women; mean age, 51.5 years; range, 30-75 years) with atypical chest pain from the emergency department were scanned using a triple rule-out protocol on a 64-slice CT scanner. Pulmonary enhancement was compared with 50 patients (21 men, 29 women; mean age, 65.6 years; range, 38-90 years) imaged with a single-phase 16-slice pulmonary angiography protocol. Aortic enhancement was compared with 24 patients (12 men, 12 women; mean age, 66.1; range, 34-92 years) who were imaged with a 16-slice aortic dissection CTA protocol and to 25 patients (15 men, 10 women; mean age, 50.8 years; range, 20-83 years) imaged with a 10-slice aortic dissection CTA protocol. A 2-tailed Student t test or sign test was used to assess significant differences from a vascular attenuation cutoff value of 250 Hounsfield units (HU). RESULTS: Individual mean pulmonary arterial and aortic attenuation values were statistically significantly less than 250 HU for the 16- and 10-slice protocols and statistically significantly more than 250 HU for the 64-slice protocols (P < 0.05). Mean pooled pulmonary attenuation values were more than 250 HU in 18% (9/50) of the 16-slice and in 93% (39/42) of the 64-slice protocols. Mean pooled aortic attenuation values were more than 250 HU in 18.4% (9/49) of the 10- and 16- and in 100% (42/42) of the 64-slice protocols. CONCLUSIONS: The triple rule-out 64-slice biphasic injection breath hold CTA protocol provides significantly higher attenuation of aortic and pulmonary vasculature compared with our current 10- and 16-slice protocols.
Ahmad Haidary; Kostaki Bis; Thomas Vrachliotis; Thomas Vrachiolitis; Rajni Kosuri; Mamtha Balasubramaniam
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  31     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2007 Nov-Dec
Date Detail:
Created Date:  2007-11-28     Completed Date:  2008-01-24     Revised Date:  2008-06-16    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  917-23     Citation Subset:  IM    
William Beaumont Hospital, Royal Oak, MI 48073, USA.
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MeSH Terms
Aged, 80 and over
Aneurysm, Dissecting / radiography
Angiography / methods*
Aortic Aneurysm, Thoracic / radiography
Aortography / methods*
Chest Pain / radiography
Contrast Media
Coronary Angiography / methods
Image Processing, Computer-Assisted / methods*
Iohexol / diagnostic use
Lung / blood supply*,  radiography
Middle Aged
Prospective Studies
Pulmonary Artery / radiography
Pulmonary Embolism / radiography
Radiographic Image Enhancement / methods*
Retrospective Studies
Tomography, X-Ray Computed / methods*
Triiodobenzoic Acids / diagnostic use
Reg. No./Substance:
0/Contrast Media; 0/Triiodobenzoic Acids; 66108-95-0/Iohexol; 92339-11-2/iodixanol
Erratum In:
J Comput Assist Tomogr. 2008 May-Jun;32(3):496
Note: Vrachiolitis, Thomas [corrected to Vrachliotis, Thomas]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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