Document Detail


Enhancement patterns of small hepatocellular carcinoma shown by dynamic MRI and CT.
MedLine Citation:
PMID:  14607719     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To study prospectively the enhancement features of small hepatocellular carcinoma (SHCC) with multi-phase scanning of dynamic MRI and spiral CT, and discuss the superiority of dynamic MRI to spiral CT. METHODS: Multi-phase dynamic contrast scanning of high field MRI and spiral CT were performed in 53 patients with SHCC. The arterial phase, portal venous phase and delayed phase scanning of spiral CT was done after the pre-contrast scanning of the entire liver. MRI was performed with SE sequence and fast multiplanar spoiled gradient-recalled sequence dynamic multi-phase contrast scanning. RESULTS: Seventy-six lesions were found in all 53 patients. Sixty-nine and 54 of the 76 lesions enhanced obviously in MRI and spiral CT arterial phase scanning respectively. The typical enhancement patterns of SHCC in the arterial phase, portal venous phase and delayed phase scanning of MRI and spiral CT were hyper-hypo-hypointense (dense) and hyper-iso-hypointense (dense). Atypical enhancement patterns were hyper-hyper-hyperintense (dense), hyper-iso-isointense (dense) and hypo-hypo-hypointense (dense). CONCLUSIONS: Both MRI and spiral CT multi-phase dynamic contrast-enhanced scanning could demonstrate the enhancement features of SHCC, and arterial phase scan of MRI was superior to spiral CT in reflecting the hypervascular characterization of SHCC. In addition, MRI was better than spiral CT in characterization of hepatic lesions combined with SE sequence.
Authors:
Fu-Hua Yan; Ji-Zhang Shen; Ren-Chen Li; Meng-Su Zeng; Dong Wu; Kang-Rong Zhou; Jun Yang; Jing-Shan Gong; Wei-Bin Shi
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hepatobiliary & pancreatic diseases international : HBPD INT     Volume:  1     ISSN:  1499-3872     ISO Abbreviation:  HBPD INT     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2003-11-10     Completed Date:  2004-05-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101151457     Medline TA:  Hepatobiliary Pancreat Dis Int     Country:  China    
Other Details:
Languages:  eng     Pagination:  420-4     Citation Subset:  IM    
Affiliation:
Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China. yanfuhua@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Carcinoma, Hepatocellular / diagnosis*
Contrast Media
Female
Humans
Image Enhancement*
Liver Neoplasms / diagnosis*
Magnetic Resonance Imaging*
Male
Middle Aged
Tomography, Spiral Computed*
Chemical
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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