| Enhancement of neutrophil function for treatment of neonatal infections. | |
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MedLine Citation:
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PMID: 2664694 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Newborn infants are at increased risk of morbidity and mortality from infection despite the continued development of new antibiotics. Because impairment of such host defense mechanisms as PMN function is thought to be largely responsible for this problem, correction of these defects in neonates offers a new and potentially important therapy against infection. Further studies are necessary to determine whether transfusion of either adult PMNs, antibody or fresh frozen plasma; administration of immunomodulating drugs; or some combination of these will provide maximum therapeutic benefit for the newborn infant with infection. |
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Authors:
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P J Krause; V C Herson; L Eisenfeld; G M Johnson |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 8 ISSN: 0891-3668 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 1989 Jun |
Date Detail:
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Created Date: 1989-08-17 Completed Date: 1989-08-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 382-9 Citation Subset: IM |
Affiliation:
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Division of Pediatric Infectious Diseases, Hartford Hospital, CT 06115. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Immunotherapy Infant, Newborn Infant, Newborn, Diseases / immunology, therapy* Neutrophils / immunology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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