| Enhancement of neural stochastic firing in cochlear implant stimulation by the addition of noise: a computational study of the influence of stimulation settings and spontaneous activity. | |
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MedLine Citation:
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PMID: 20471638 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is known that, in cochlear implants (CIs), the addition of noise to CI stimuli may enhance the stochastic firing in the auditory nerve (AN). The aim of this study was to investigate, by using a model of a fiber of the AN the influence of CI stimulation settings (i.e., stimulation rate and stimulus magnitude) and fiber spontaneous activity on the enhancement of stochastic firing when CI stimuli are combined with noise. Results showed that the stimulation rate had an effect on the enhancement of stochastic firing in the AN, whereas the stimulus magnitude and the spontaneous firing rate had no influence. |
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Authors:
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Alessia Paglialonga; Serena Fiocchi; Paolo Ravazzani; Gabriella Tognola |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-14 |
Journal Detail:
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Title: Computers in biology and medicine Volume: 40 ISSN: 1879-0534 ISO Abbreviation: Comput. Biol. Med. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-10 Completed Date: 2010-09-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1250250 Medline TA: Comput Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 597-606 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Istituto di Ingegneria Biomedica, Consiglio Nazionale delle Ricerche, ISIB-CNR, Piazza Leonardo da Vinci 32, I-20133 Milano, Italy. alessia.paglialonga@polimi.it |
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| MeSH Terms | |
Descriptor/Qualifier:
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Action Potentials
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physiology* Cochlear Implants* Cochlear Nerve / physiology* Computational Biology Computer Simulation* Electric Stimulation Humans Models, Neurological* Stochastic Processes |
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