Document Detail


Enhancement of neural stochastic firing in cochlear implant stimulation by the addition of noise: a computational study of the influence of stimulation settings and spontaneous activity.
MedLine Citation:
PMID:  20471638     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is known that, in cochlear implants (CIs), the addition of noise to CI stimuli may enhance the stochastic firing in the auditory nerve (AN). The aim of this study was to investigate, by using a model of a fiber of the AN the influence of CI stimulation settings (i.e., stimulation rate and stimulus magnitude) and fiber spontaneous activity on the enhancement of stochastic firing when CI stimuli are combined with noise. Results showed that the stimulation rate had an effect on the enhancement of stochastic firing in the AN, whereas the stimulus magnitude and the spontaneous firing rate had no influence.
Authors:
Alessia Paglialonga; Serena Fiocchi; Paolo Ravazzani; Gabriella Tognola
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-05-14
Journal Detail:
Title:  Computers in biology and medicine     Volume:  40     ISSN:  1879-0534     ISO Abbreviation:  Comput. Biol. Med.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-10     Completed Date:  2010-09-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1250250     Medline TA:  Comput Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  597-606     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Istituto di Ingegneria Biomedica, Consiglio Nazionale delle Ricerche, ISIB-CNR, Piazza Leonardo da Vinci 32, I-20133 Milano, Italy. alessia.paglialonga@polimi.it
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MeSH Terms
Descriptor/Qualifier:
Action Potentials / physiology*
Cochlear Implants*
Cochlear Nerve / physiology*
Computational Biology
Computer Simulation*
Electric Stimulation
Humans
Models, Neurological*
Stochastic Processes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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