Document Detail

Enhanced ultrafiltration using 7.5% icodextrin/1.36% glucose combination dialysate: a pilot study.
MedLine Citation:
PMID:  15559483     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: A pilot study to compare the use of a combination dialysate (7.5% icodextrin/1.36% glucose) versus icodextrin 7.5% alone for the long dwell in patients on peritoneal dialysis (PD). DESIGN: A 4-week, prospective, randomized crossover study. SETTING: A large regional renal unit providing treatment for a population of 1.7 million. PATIENTS: Five patients on continuous ambulatory PD (CAPD) and 3 patients on automated PD. MAIN OUTCOME MEASUREMENTS: Long-dwell and 24-hour ultrafiltration volumes, body weight, 24-hour ambulatory blood pressure, and antihypertensive/diuretic tablet count. RESULTS: The use of the combination dialysate resulted in an increase in the median (interquartile range) long-dwell ultrafiltration, from 750 (650-828) mL to 1000 (889-1100) mL (p < 0.001), and 24-hour ultrafiltration, from 739 (400-1623) mL to 956 (700-1750) mL (p < 0.001). Weight, blood pressure, and tablet count remained unchanged. CONCLUSIONS: The use of the novel combination dialysate resulted in a 33% increase in long-dwell ultrafiltration and a 29% increase in 24-hour ultrafiltration.
Fiona Dallas; Sarah B Jenkins; Martin E Wilkie
Related Documents :
751433 - Computer assisted monitoring in intensive medicine.
8339453 - Assessing hypertension management: the role of 24-hour blood pressure monitoring.
1922223 - Prevention of high-altitude pulmonary edema by nifedipine.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  24     ISSN:  0896-8608     ISO Abbreviation:  Perit Dial Int     Publication Date:    2004 Nov-Dec
Date Detail:
Created Date:  2004-11-22     Completed Date:  2005-02-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  542-6     Citation Subset:  IM    
Sheffield Kidney Institute, Sheffield, United Kingdom.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cross-Over Studies
Dialysis Solutions* / administration & dosage,  chemistry
Glucans / administration & dosage*
Glucose / administration & dosage*
Middle Aged
Peritoneal Dialysis*
Peritoneal Dialysis, Continuous Ambulatory*
Pilot Projects
Prospective Studies
Time Factors
Reg. No./Substance:
0/Dialysis Solutions; 0/Glucans; 0/icodextrin; 50-99-7/Glucose
Comment In:
Perit Dial Int. 2004 Nov-Dec;24(6):501-3   [PMID:  15559472 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Factors affecting the use of peritoneal dialysis among the ESRD population in India: a single-center...
Next Document:  Bimodal dialysis: an integrated approach to renal replacement therapy.