| Enhanced ultrafiltration using 7.5% icodextrin/1.36% glucose combination dialysate: a pilot study. | |
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MedLine Citation:
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PMID: 15559483 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: A pilot study to compare the use of a combination dialysate (7.5% icodextrin/1.36% glucose) versus icodextrin 7.5% alone for the long dwell in patients on peritoneal dialysis (PD). DESIGN: A 4-week, prospective, randomized crossover study. SETTING: A large regional renal unit providing treatment for a population of 1.7 million. PATIENTS: Five patients on continuous ambulatory PD (CAPD) and 3 patients on automated PD. MAIN OUTCOME MEASUREMENTS: Long-dwell and 24-hour ultrafiltration volumes, body weight, 24-hour ambulatory blood pressure, and antihypertensive/diuretic tablet count. RESULTS: The use of the combination dialysate resulted in an increase in the median (interquartile range) long-dwell ultrafiltration, from 750 (650-828) mL to 1000 (889-1100) mL (p < 0.001), and 24-hour ultrafiltration, from 739 (400-1623) mL to 956 (700-1750) mL (p < 0.001). Weight, blood pressure, and tablet count remained unchanged. CONCLUSIONS: The use of the novel combination dialysate resulted in a 33% increase in long-dwell ultrafiltration and a 29% increase in 24-hour ultrafiltration. |
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Authors:
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Fiona Dallas; Sarah B Jenkins; Martin E Wilkie |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis Volume: 24 ISSN: 0896-8608 ISO Abbreviation: Perit Dial Int Publication Date: 2004 Nov-Dec |
Date Detail:
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Created Date: 2004-11-22 Completed Date: 2005-02-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8904033 Medline TA: Perit Dial Int Country: Canada |
Other Details:
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Languages: eng Pagination: 542-6 Citation Subset: IM |
Affiliation:
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Sheffield Kidney Institute, Sheffield, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cross-Over Studies Dialysis Solutions* / administration & dosage, chemistry Female Glucans / administration & dosage* Glucose / administration & dosage* Humans Male Middle Aged Peritoneal Dialysis* Peritoneal Dialysis, Continuous Ambulatory* Pilot Projects Prospective Studies Time Factors Ultrafiltration |
| Chemical | |
Reg. No./Substance:
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0/Dialysis Solutions; 0/Glucans; 0/icodextrin; 50-99-7/Glucose |
| Comments/Corrections | |
Comment In:
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Perit Dial Int. 2004 Nov-Dec;24(6):501-3
[PMID:
15559472
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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