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Enhanced production of pigments by addition of surfactants in submerged fermentation of Monascus purpureus H1102.
MedLine Citation:
PMID:  23595359     Owner:  NLM     Status:  Publisher    
BACKGROUND: The production of pigment by Monascus has attracted increasing attentions. Modification of cell membrane structure by addition of surfactant has been proved to be effective for the secretion of intracellular metabolites. Hence, the effects and underlying mechanism of surfactants on the production of pigments in submerged fermentation of Monascus purpureus H1102 were systematically investigated. RESULTS: Various surfactants exerted significant but different impacts on the biomass and production of pigments. The maximum production of pigment (304.3 U mL(-1) ) and the highest extracellular pigment to intracellular pigment ratio (1.46) were achieved when 15 g L(-1) Triton X-100 was added at the 24(th) h of the fermentation, corresponding to 88.4% and 240% significant increase as compared with that of the control, respectively. Meanwhile, the concentration of citrinin (0.94 mg L(-1) ) was 20.6% lower than that of the control. A further study on the fatty acid composition of M. purpureus H1102 showed that the ratio of unsaturated/saturated fatty acids and the index of unsaturated fatty acid significantly increased with the addition of Triton X-100. CONCLUSION: The addition of surfactant Triton X-100 could greatly enhance the production of pigment. It was suggested that Triton X-100 facilitated the secretion of intracellular pigment and therefore enhanced the pigment production accordingly.
Yonghui Wang; Bobo Zhang; Liping Lu; Yan Huang; Ganrong Xu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-4-17
Journal Detail:
Title:  Journal of the science of food and agriculture     Volume:  -     ISSN:  1097-0010     ISO Abbreviation:  J. Sci. Food Agric.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-4-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376334     Medline TA:  J Sci Food Agric     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.
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