Document Detail

Enhanced oxidative stability of a hydrophilic arginine-conjugated linoleic acid complex.
MedLine Citation:
PMID:  15630300     Owner:  NLM     Status:  MEDLINE    
The application of conjugated linoleic acid (CLA) as a functional food ingredient has been limited due to its high cost of purification and insolubility in water. Recently, we reported a method to produce high-purity CLA using two-step urea-inclusion crystallization and a hydrophilic arginine-CLA (Arg-CLA) complex. The present study compared the oxidative stability and antioxidant activity of CLA and Arg-CLA. Hydroperoxide production from CLA increased about 12-fold at 10 hr after heat treatment at 100(R)C, whereas Arg-CLA did not exhibit significant hydroperoxide production. Furthermore, the Arg-CLA complex showed synergistic antioxidant activity in a 2,2'-azinobis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) radical scavenging assay. Arg-CLA at 20 mM scavenged 89% of ABTS radicals in 3 h, whereas CLA alone quenched only 48% under the same conditions. Our results indicate that a hydrophilic Arg-CLA exhibits enhanced oxidative stability and antioxidant activity, which could expand the scope of CLA application in various food industries.
Ki Won Lee; Young Jun Kim; Seong-Kweon Lee; Hyong Joo Lee
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BioFactors (Oxford, England)     Volume:  22     ISSN:  0951-6433     ISO Abbreviation:  Biofactors     Publication Date:  2004  
Date Detail:
Created Date:  2005-01-04     Completed Date:  2005-04-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807441     Medline TA:  Biofactors     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  299-301     Citation Subset:  IM    
Department of Food Science and Technology, School of Agricultural Biotechnology, Seoul National University, Seoul 151-742, South Korea.
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MeSH Terms
Antioxidants / analysis
Food Analysis
Linoleic Acids, Conjugated* / chemical synthesis
Reg. No./Substance:
0/Antioxidants; 0/Linoleic Acids, Conjugated; 74-79-3/Arginine

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